Global sales for Prolia dropped by $372M in Q1 2026 compared to Q1 2025, driven by a 17% volume decline and increased competition from biosimilars following patent expirations. The company expects this sales erosion to accelerate.
Filing excerpt
The decrease in global Prolia sales for the three months ended March 31, 2026 was primarily driven by lower volume of 17%, lower net selling price of 10% and 4% from lower inventory.
What this signalsFilings often name leadership changes, deals and spending plans.
Regions named
sec-10qmarketShareLossGet every 10-Q signal for Amgen and the companies you sell to, in the tools you already use.
Connect Autobound to Claude, Claude Code or Cursor with MCP. Then ask: “What changed at Amgen this week?”
The Signal API returns 10-Q signals for any list of companies as JSON, for your CRM, warehouse or app.
Sign up and spend your free credits on the companies you sell to.
This page shows a preview. The full sec-10q record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.
Company
linkedin_urlValue in the APIindustriesValue in the APIemployee_count_lowValue in the APIemployee_count_highValue in the APIrevenueValue in the APIdescriptionValue in the APISignal
signal_nameValue in the APIassociationValue in the APIGET /v1/signals/5a0da686-6a88-45be-9a9d-373a5744fe85 returns this record as JSON. POST /v1/companies/enrich returns every signal for amgen.com.
{
"signal_id": "5a0da686-6a88-45be-9a9d-373a5744fe85",
"signal_type": "sec-10q",
"signal_subtype": "marketShareLoss",
"detected_at": "2026-05-05T08:48:22.11+00:00",
"company": {
"name": "Amgen",
"domain": "amgen.com"
},
"data": {
"detail": "Global sales for Prolia dropped by $372M in Q1 2026 compared to Q1 2025, driven by a 17% volume decline and increased competition from biosimilars following patent expirations. The company expects this sales erosion to accelerate.",
"metrics": {
"pct": -34,
"timeframe": "current_quarter",
"pct_context": "Total Prolia sales change YoY",
"dollar_context": "Decline in Total Prolia sales vs prior year quarter ($1,099M to $727M)",
"dollar_millions": -372
},
"summary": "Prolia sales plummet 34% YoY due to biosimilar competition and patent expiry",
"excerpts": "The decrease in global Prolia sales for the three months ended March 31, 2026 was primarily driven by lower volume of 17%, lower net selling price of 10% and 4% from lower inventory.",
"relevance": 0.9,
"sentiment": "negative",
"confidence": "high",
"source_url": "https://www.sec.gov/Archives/edgar/data/318154/000031815426000057/amgn-20260331.htm",
"filing_date": "2026-04-30",
"filing_year": 2026,
"fiscal_year": 0,
"fiscal_year_end": "03/31",
"sales_relevance": "Urgency to improve",
"signal_category": "market",
"regions_mentioned": [
"U.S.",
"ROW",
"Europe"
]
}
}
curl https://signals.autobound.ai/v1/signals/5a0da686-6a88-45be-9a9d-373a5744fe85 \
-H "X-API-KEY: $AUTOBOUND_API_KEY"curl -X POST https://signals.autobound.ai/v1/companies/enrich \
-H "X-API-KEY: $AUTOBOUND_API_KEY" \
-H "Content-Type: application/json" \
-d '{"domain":"amgen.com","limit":20}'Long text fields are shortened on this page.
Looking up one signal by its id is free. Enrich costs 2 credits per signal returned; a call with no results is free.