Skip to main content
AstraZenecaPatent grant

AstraZeneca was granted a patent for compounds targeting FAP-related conditions.

What happened

In September 2026 AstraZeneca patented quinoline carboxamide compounds for pharmaceutical use against conditions involving fibroblast activation protein, including potential diagnostic or treatment applications.

Source

Abstract

Compounds having the structure of Formula (I): and pharmaceutically acceptable salts thereof, wherein R 2, R 3, R 5, R 6, R 7, and R 8 are as defined in the specification; pharmaceutical compositions comprising such compounds and salts; use of such compounds and salts to treat or prevent Prolyl endopeptidase fibroblast activation protein (FAP)-mediated conditions; kits comprising such compounds and salts; and methods for manufacturing such compounds and salts.

patents.google.com/patent/US12747223Read the full source

Extracted by Autobound

From the Signal API record
Signal
Patent grant

What this signalsA new patent often shows where a company is putting its R&D budget.

Grant date
Sep 29, 2026
Inventors
4
Patent number
US12747223
Assignee
AstraZeneca AB

The full record

From the Signal API record

People

  • Jonas BrånaltInventor
  • Maria JohanssonInventor
  • Anneli NordqvistInventor
  • Gavin O'MahonyInventor
  • Marianne SwansonInventor

Details

Primary CPC class
C07D 401/12
USPTO assignee
AstraZeneca AB
What the invention does
A family of drug-like molecules designed to block FAP activity, with related formulations, manufacturing methods, and treatment uses.

Topics and mentions

Tags

  • Intellectual Property
  • Research & Development
  • Pharmaceuticals
  • Medical Research

Technologies named

  • medicinal chemistry
  • small-molecule therapeutics
  • FAP inhibitors
  • pharmaceutical formulations

Extraction

Detected
Sep 30, 2026
signal_type
patents-company
signal_subtype
patentGrant

Use this data

Get every patent signal for AstraZeneca and the companies you sell to, in the tools you already use.

  1. Ask Claude about it

    Connect Autobound to Claude, Claude Code or Cursor with MCP. Then ask: “What changed at AstraZeneca this week?”

  2. Send it to your own tools

    The Signal API returns patent signals for any list of companies as JSON, for your CRM, warehouse or app.

  3. Try it free

    Sign up and spend your free credits on the companies you sell to.

    Start Free1,000 free credits

The API returns more than this page shows

This page shows a preview. The full patents-company record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.

Company

  • linkedin_urlValue in the API
  • industriesValue in the API
  • employee_count_lowValue in the API
  • employee_count_highValue in the API
  • revenueValue in the API
  • descriptionValue in the API

Signal

  • signal_nameValue in the API
  • associationValue in the API
Show the full JSONThe record on this page and the API request

GET /v1/signals/52abe794-1e3c-52fb-a455-a5394372c1a2 returns this record as JSON. POST /v1/companies/enrich returns every signal for astrazeneca.com.

{
  "signal_id": "52abe794-1e3c-52fb-a455-a5394372c1a2",
  "signal_type": "patents-company",
  "signal_subtype": "patentGrant",
  "detected_at": "2026-09-30T16:57:43+00:00",
  "company": {
    "name": "AstraZeneca",
    "domain": "astrazeneca.com"
  },
  "data": {
    "cpc": [
      {
        "code": "C07D 401/12"
      }
    ],
    "tags": [
      "Intellectual Property",
      "Research & Development",
      "Pharmaceuticals",
      "Medical Research"
    ],
    "detail": "In September 2026 AstraZeneca patented quinoline carboxamide compounds for pharmaceutical use against conditions involving fibroblast activation protein, including potential diagnostic or treatment applications.",
    "summary": "AstraZeneca was granted a patent for compounds targeting FAP-related conditions.",
    "event_at": "2026-09-29",
    "inventors": [
      {
        "name": "Jonas Brånalt",
        "status": "resolved",
        "is_primary": true,
        "linkedin_url": "https://www.linkedin.com/in/jonas-br%C3%A5nalt-a374bb49"
      },
      {
        "name": "Maria Johansson",
        "status": "unresolved",
        "is_primary": false
      },
      {
        "name": "Anneli Nordqvist",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/anneli-nordqvist-71b69b42"
      },
      {
        "name": "Gavin O'Mahony",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/gavin-o-mahony-bb498545"
      },
      {
        "name": "Marianne Swanson",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/marianne-swanson-39406948"
      }
    ],
    "event_kind": "grant_date",
    "grant_date": "2026-09-29",
    "source_url": "https://patents.google.com/patent/US12747223",
    "cpc_primary": {
      "code": "C07D 401/12"
    },
    "patent_title": "N-(2-(3-cyano-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)quinoline-4-carboxamides",
    "patent_number": "US12747223",
    "uspto_assignee": "AstraZeneca AB",
    "patent_abstract": "Compounds having the structure of Formula (I): and pharmaceutically acceptable salts thereof, wherein R 2 , R 3 , R 5 , R 6 , R 7 , and R 8 are as defined in the specification; pharmaceutical compositions comprising such compounds and salts; use of such compounds and salts to treat or prevent Prolyl endopeptidase fibroblast activation protein (FAP)-mediated conditions; kits comprising such compounds and salts; and methods for manufacturing such compounds and salts.",
    "precision_class": "structural",
    "invention_explanation": "A family of drug-like molecules designed to block FAP activity, with related formulations, manufacturing methods, and treatment uses.",
    "technologies_mentioned": [
      "medicinal chemistry",
      "small-molecule therapeutics",
      "FAP inhibitors",
      "pharmaceutical formulations"
    ]
  }
}

Long text fields are shortened on this page.

Looking up one signal by its id is free. Enrich costs 2 credits per signal returned; a call with no results is free.