US patent US12747223
N-(2-(3-cyano-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)quinoline-4-carboxamides
Abstract
Compounds having the structure of Formula (I): and pharmaceutically acceptable salts thereof, wherein R 2, R 3, R 5, R 6, R 7, and R 8 are as defined in the specification; pharmaceutical compositions comprising such compounds and salts; use of such compounds and salts to treat or prevent Prolyl endopeptidase fibroblast activation protein (FAP)-mediated conditions; kits comprising such compounds and salts; and methods for manufacturing such compounds and salts.