Bio-Techne and Refeyn close critical gap in bispecific antibody and biosimilar characterization.
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Bio-Techne and Refeyn close critical gap in bispecific antibody and biosimilar characterization. * New integrated workflow combines icIEF fractionation and mass photometry * Enables direct characterization of aggregation and size within icIEF-resolved charge variants * Four-hour workflow reduces development risk and accelerates biosimilar manufacturing MINNEAPOLIS and OXFORD, England, June 4, 2026 /PRNewswire/ - Bio-Techne Corporation (NASDAQ: TECH), a global provider of life science tools, reagents and diagnostic products, and Refeyn, the pioneer in mass photometry technology, today announced a first-of-its-kind integrated workflow for the characterization of charge and size variants in bispecific antibodies and biosimilars. By combining R&D Systems MauriceFlex(TM) imaged capillary isoelectric focusing (icIEF) fractionation system with Refeyn's TwoMP mass photometry platform, researchers can directly correlate charge heterogeneity with molecular weight and aggregation at single-molecule resolution in a streamlined four-hour workflow. Bispecific antibodies are among the fastest-growing classes of biotherapeutics, but their structural complexity makes thorough characterization challenging. Incomplete characterization can delay development, increase manufacturing risk, and lead to costly late-stage failures. The MauriceFlex(TM) system delivers high-resolution separation...
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