The company highlights that insufficient tissue sample quality can lead to NGS test failure (QNS), a significant problem in diagnostics. Their liquid biopsy solutions are positioned to solve this, indicating a focus on technologies that improve test success rates and data quality.
Filing excerpt
Small quantities or low quality of tissue from an inaccessible biopsy site can lead to a Quantity Not Sufficient (“QNS”) result when NGS fails for lack of input material.
What this signalsFilings often name leadership changes, deals and spending plans.
Technologies
sec-10kqualityIssueGet every 10-K signal for Caris Life Sciences and the companies you sell to, in the tools you already use.
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This page shows a preview. The full sec-10k record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.
Company
linkedin_urlValue in the APIindustriesValue in the APIemployee_count_lowValue in the APIemployee_count_highValue in the APIrevenueValue in the APIdescriptionValue in the APISignal
signal_nameValue in the APIassociationValue in the APIGET /v1/signals/581c3c49-afca-4ff5-932f-9c7a5c764d60 returns this record as JSON. POST /v1/companies/enrich returns every signal for carislifesciences.com.
{
"signal_id": "581c3c49-afca-4ff5-932f-9c7a5c764d60",
"signal_type": "sec-10k",
"signal_subtype": "qualityIssue",
"detected_at": "2026-03-10T06:44:07.681+00:00",
"company": {
"name": "Caris Life Sciences",
"domain": "carislifesciences.com"
},
"data": {
"detail": "The company highlights that insufficient tissue sample quality can lead to NGS test failure (QNS), a significant problem in diagnostics. Their liquid biopsy solutions are positioned to solve this, indicating a focus on technologies that improve test success rates and data quality.",
"summary": "Identifies 'Quantity Not Sufficient' (QNS) results as a key failure point in tissue profiling",
"excerpts": "Small quantities or low quality of tissue from an inaccessible biopsy site can lead to a Quantity Not Sufficient (“QNS”) result when NGS fails for lack of input material.",
"relevance": 0.7,
"sentiment": "negative",
"confidence": "high",
"source_url": "https://www.sec.gov/Archives/edgar/data/2019410/000201941026000016/cai-20251231.htm",
"filing_date": "2026-03-03",
"filing_year": 2026,
"fiscal_year_end": "12/31",
"sales_relevance": "Quality management needed",
"signal_category": "operations",
"technologies_mentioned": [
"NGS"
]
}
}
curl https://signals.autobound.ai/v1/signals/581c3c49-afca-4ff5-932f-9c7a5c764d60 \
-H "X-API-KEY: $AUTOBOUND_API_KEY"curl -X POST https://signals.autobound.ai/v1/companies/enrich \
-H "X-API-KEY: $AUTOBOUND_API_KEY" \
-H "Content-Type: application/json" \
-d '{"domain":"carislifesciences.com","limit":20}'Long text fields are shortened on this page.
Looking up one signal by its id is free. Enrich costs 2 credits per signal returned; a call with no results is free.