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Caris Life SciencesPatent grant

Caris MPI was granted a patent for predicting platinum chemotherapy response.

What happened

In September 2026 Caris MPI patented a cancer-treatment response tool for oncology care, using molecular patient data to support chemotherapy decisions.

Source

patents.google.comSep 8, 2026

US patent US12731666

Pan-cancer platinum response predictor

Abstract

Comprehensive molecular profiling provides a wealth of data concerning the molecular status of patient samples. Such data can be compared to patient response to treatments to identify biomarker signatures that predict response or non-response to such treatments. This approach has been applied to identify biomarker signatures that correlate with response of cancer patients to platinum-based chemotherapy. Described herein are data structures, data processing, and machine learning models to predict a probability of benefit of a treatment for a disease or disorder of a subject having a particular set of biomarkers, as well as an exemplary application of such a model to precision medicine, e.g., to methods for selecting a treatment based on a molecular profile, e.g., a treatment comprising platinum therapy.

patents.google.com/patent/US12731666Read the full source

Extracted by Autobound

From the Signal API record
Signal
Patent grant

What this signalsA new patent often shows where a company is putting its R&D budget.

Grant date
Sep 8, 2026
Inventors
3
Tech area
health tech / medical informatics
Patent number
US12731666

The full record

From the Signal API record

People

  • Jim AbrahamInventor
  • Wolfgang Michael KornInventor
  • David SpetzlerInventor

Details

Primary CPC class
G16H 20/10 (Healthcare informatics (ICT for medical/healthcare data))
USPTO assignee
Caris MPI, Inc.
What the invention does
A machine-learning method that studies tumor molecular patterns to estimate whether a patient’s cancer will respond to platinum-based chemotherapy.

Topics and mentions

Tags

  • Intellectual Property
  • Research & Development
  • Healthcare Technology
  • Artificial Intelligence
  • Machine Learning

Technologies named

  • precision oncology
  • molecular profiling
  • machine learning
  • clinical decision support

Extraction

Detected
Sep 15, 2026
signal_type
patents-company
signal_subtype
patentGrant

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This page shows a preview. The full patents-company record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.

Company

  • linkedin_urlValue in the API
  • industriesValue in the API
  • employee_count_lowValue in the API
  • employee_count_highValue in the API
  • revenueValue in the API
  • descriptionValue in the API

Signal

  • signal_nameValue in the API
  • associationValue in the API
Show the full JSONThe record on this page and the API request

GET /v1/signals/16d024f7-1598-5f42-b173-835bf39015ce returns this record as JSON. POST /v1/companies/enrich returns every signal for carislifesciences.com.

{
  "signal_id": "16d024f7-1598-5f42-b173-835bf39015ce",
  "signal_type": "patents-company",
  "signal_subtype": "patentGrant",
  "detected_at": "2026-09-15T03:24:34+00:00",
  "company": {
    "name": "Caris Life Sciences",
    "domain": "carislifesciences.com"
  },
  "data": {
    "cpc": [
      {
        "code": "G16H 20/10",
        "label": "Healthcare informatics (ICT for medical/healthcare data)"
      },
      {
        "code": "G06N 3/084",
        "label": "Computing arrangements based on specific computational models"
      },
      {
        "code": "G06N 20/00",
        "label": "Computing arrangements based on specific computational models"
      },
      {
        "code": "G16H 10/60",
        "label": "Healthcare informatics (ICT for medical/healthcare data)"
      },
      {
        "code": "G16H 50/20",
        "label": "Healthcare informatics (ICT for medical/healthcare data)"
      }
    ],
    "tags": [
      "Intellectual Property",
      "Research & Development",
      "Healthcare Technology",
      "Artificial Intelligence",
      "Machine Learning"
    ],
    "detail": "In September 2026 Caris MPI patented a cancer-treatment response tool for oncology care, using molecular patient data to support chemotherapy decisions.",
    "summary": "Caris MPI was granted a patent for predicting platinum chemotherapy response.",
    "event_at": "2026-09-08",
    "inventors": [
      {
        "name": "Jim Abraham",
        "status": "resolved",
        "is_primary": true,
        "linkedin_url": "https://www.linkedin.com/in/jimpabraham"
      },
      {
        "name": "Wolfgang Michael Korn",
        "status": "unresolved",
        "is_primary": false
      },
      {
        "name": "David Spetzler",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/david-spetzler-397a407"
      }
    ],
    "tech_area": "health tech / medical informatics",
    "event_kind": "grant_date",
    "grant_date": "2026-09-08",
    "source_url": "https://patents.google.com/patent/US12731666",
    "cpc_primary": {
      "code": "G16H 20/10",
      "label": "Healthcare informatics (ICT for medical/healthcare data)"
    },
    "patent_title": "Pan-cancer platinum response predictor",
    "patent_number": "US12731666",
    "uspto_assignee": "Caris MPI, Inc.",
    "patent_abstract": "Comprehensive molecular profiling provides a wealth of data concerning the molecular status of patient samples. Such data can be compared to patient response to treatments to identify biomarker signatures that predict response or non-response to such treatments. This approach has been applied to identify biomarker signatures that correlate with response of cancer patients to platinum-based chemotherapy. Described herein are data structures, data processing, and machine learning models to predict a probability of benefit of a treatment for a disease or disorder of a subject having a particular set of biomarkers, as well as an exemplary application of such a model to precision medicine, e.g., to methods for selecting a treatment based on a molecular profile, e.g., a treatment comprising platinum therapy.",
    "precision_class": "structural",
    "invention_explanation": "A machine-learning method that studies tumor molecular patterns to estimate whether a patient’s cancer will respond to platinum-based chemotherapy.",
    "technologies_mentioned": [
      "precision oncology",
      "molecular profiling",
      "machine learning",
      "clinical decision support"
    ]
  }
}

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