In September 2026 GE Healthcare patented a chemical process for producing iopamidol, a contrast agent used in diagnostic medical imaging.
Abstract
The present invention provides a process for the preparation of a compound of Formula (II): wherein the process comprises: (i) reacting a compound of Formula (I) with pyridine and 2-acetyloxypropanoyl chloride (APC) to give a compound of Formula (II), wherein the compound of Formula (I) has the following structure:
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Company
linkedin_urlValue in the APIindustriesValue in the APIemployee_count_lowValue in the APIemployee_count_highValue in the APIrevenueValue in the APIdescriptionValue in the APISignal
signal_nameValue in the APIassociationValue in the APIGET /v1/signals/0673b558-8bca-5f63-a9ee-6d41d66ddb79 returns this record as JSON. POST /v1/companies/enrich returns every signal for gehealthcare.com.
{
"signal_id": "0673b558-8bca-5f63-a9ee-6d41d66ddb79",
"signal_type": "patents-company",
"signal_subtype": "patentGrant",
"detected_at": "2026-09-23T14:50:05+00:00",
"company": {
"name": "GE HealthCare",
"domain": "gehealthcare.com"
},
"data": {
"cpc": [
{
"code": "C07C 231/02"
},
{
"code": "C07C 237/46"
},
{
"code": "C07C 231/02"
},
{
"code": "C07C 237/46"
}
],
"tags": [
"Intellectual Property",
"Research & Development",
"Healthcare Technology",
"Chemical Engineering"
],
"detail": "In September 2026 GE Healthcare patented a chemical process for producing iopamidol, a contrast agent used in diagnostic medical imaging.",
"summary": "GE Healthcare was granted a patent for preparing iopamidol.",
"event_at": "2026-09-22",
"inventors": [
{
"name": "Martin Hennum",
"status": "resolved",
"is_primary": true,
"linkedin_url": "https://www.linkedin.com/in/martin-hennum"
},
{
"name": "Lone Aanerud Omtvedt",
"status": "unresolved",
"is_primary": false
},
{
"name": "Ole Magne Homestad",
"status": "unresolved",
"is_primary": false
},
{
"name": "Sumihar H.D. Silalahi",
"status": "resolved",
"is_primary": false,
"linkedin_url": "https://www.linkedin.com/in/sumihar-silalahi-5a8a4613"
},
{
"name": "Siw Anette Helle",
"status": "resolved",
"is_primary": false,
"linkedin_url": "https://www.linkedin.com/in/siw-anette-helle-57979662"
},
{
"name": "Mari Brusletten",
"status": "resolved",
"is_primary": false,
"linkedin_url": "https://www.linkedin.com/in/mari-brusletten-1bb995172"
},
{
"name": "Lars Terje Holmaas",
"status": "resolved",
"is_primary": false,
"linkedin_url": "https://www.linkedin.com/in/lars-terje-holmaas-a707802b"
}
],
"event_kind": "grant_date",
"grant_date": "2026-09-22",
"source_url": "https://patents.google.com/patent/US12741931",
"cpc_primary": {
"code": "C07C 231/02"
},
"patent_title": "Process for the preparation of iopamidol",
"patent_number": "US12741931",
"uspto_assignee": "GE HEALTHCARE AS",
"patent_abstract": "The present invention provides a process for the preparation of a compound of Formula (II): wherein the process comprises: (i) reacting a compound of Formula (I) with pyridine and 2-acetyloxypropanoyl chloride (APC) to give a compound of Formula (II), wherein the compound of Formula (I) has the following structure:",
"precision_class": "structural",
"invention_explanation": "A manufacturing method that reacts a starting compound with pyridine and APC to build iopamidol more directly.",
"technologies_mentioned": [
"iopamidol",
"contrast agents",
"chemical synthesis"
]
}
}
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-H "X-API-KEY: $AUTOBOUND_API_KEY" \
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