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IncytePatent grant

Incyte was granted a patent for A2A and A2B receptor inhibitors.

What happened

In September 2026 Incyte patented drug compounds designed to treat cancer and inflammatory, cardiovascular, and neurodegenerative diseases.

Source

patents.google.comSep 15, 2026

US patent US12735424

Fused pyrazine derivatives as A2A / A2B inhibitors

Abstract

This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which modulate the activity of adenosine receptors, such as subtypes A2A and A2B receptors, and are useful in the treatment of diseases related to the activity of adenosine receptors including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases.

patents.google.com/patent/US12735424Read the full source

Extracted by Autobound

From the Signal API record
Signal
Patent grant

What this signalsA new patent often shows where a company is putting its R&D budget.

Grant date
Sep 15, 2026
Patent number
US12735424
Assignee
Incyte Corporation

The full record

From the Signal API record

People

  • Xiaozhao WangInventor
  • Peter Niels CarlsenInventor
  • Pei GanInventor
  • Gia HoangInventor
  • Yong LiInventor
  • Chao QiInventor

Details

Primary CPC class
C07D 487/04
USPTO assignee
Incyte Corporation
What the invention does
A family of fused pyrazine-based compounds that blocks selected adenosine receptors, which can help alter disease-related immune and cellular activity.

Topics and mentions

Inventors

  • Xiaozhao Wang
  • Peter Niels Carlsen
  • Gia Hoang
  • Liangxing Wu

Tags

  • Intellectual Property
  • Research & Development
  • Pharmaceuticals
  • Medical Research

Technologies named

  • medicinal chemistry
  • adenosine receptor inhibitors
  • small-molecule therapeutics

Extraction

Detected
Sep 20, 2026
signal_type
patents-company
signal_subtype
patentGrant

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This page shows a preview. The full patents-company record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.

Company

  • linkedin_urlValue in the API
  • industriesValue in the API
  • employee_count_lowValue in the API
  • employee_count_highValue in the API
  • revenueValue in the API
  • descriptionValue in the API

Signal

  • signal_nameValue in the API
  • associationValue in the API
Show the full JSONThe record on this page and the API request

GET /v1/signals/762eb116-3817-5b2f-9a4a-a4d52338c0bb returns this record as JSON. POST /v1/companies/enrich returns every signal for incyte.com.

{
  "signal_id": "762eb116-3817-5b2f-9a4a-a4d52338c0bb",
  "signal_type": "patents-company",
  "signal_subtype": "patentGrant",
  "detected_at": "2026-09-20T17:42:02+00:00",
  "company": {
    "name": "Incyte",
    "domain": "incyte.com"
  },
  "data": {
    "cpc": [
      {
        "code": "C07D 487/04"
      },
      {
        "code": "C07D 519/00"
      }
    ],
    "tags": [
      "Intellectual Property",
      "Research & Development",
      "Pharmaceuticals",
      "Medical Research"
    ],
    "detail": "In September 2026 Incyte patented drug compounds designed to treat cancer and inflammatory, cardiovascular, and neurodegenerative diseases.",
    "summary": "Incyte was granted a patent for A2A and A2B receptor inhibitors.",
    "event_at": "2026-09-15",
    "inventors": [
      {
        "name": "Xiaozhao Wang",
        "status": "resolved",
        "is_primary": true,
        "linkedin_url": "https://www.linkedin.com/in/xiaozhao-wang-a747155a"
      },
      {
        "name": "Peter Niels Carlsen",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/peter-carlsen-7826aab7"
      },
      {
        "name": "Pei Gan",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/pei-gan-40a8bb10a"
      },
      {
        "name": "Gia Hoang",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/giahoang"
      },
      {
        "name": "Yong Li",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/yong-li-3b8b5413b"
      },
      {
        "name": "Chao Qi",
        "status": "unresolved",
        "is_primary": false
      },
      {
        "name": "Liangxing Wu",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/liangxing"
      },
      {
        "name": "Wenqing Yao",
        "status": "unresolved",
        "is_primary": false
      }
    ],
    "event_kind": "grant_date",
    "grant_date": "2026-09-15",
    "source_url": "https://patents.google.com/patent/US12735424",
    "cpc_primary": {
      "code": "C07D 487/04"
    },
    "patent_title": "Fused pyrazine derivatives as A2A / A2B inhibitors",
    "patent_number": "US12735424",
    "uspto_assignee": "Incyte Corporation",
    "patent_abstract": "This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which modulate the activity of adenosine receptors, such as subtypes A2A and A2B receptors, and are useful in the treatment of diseases related to the activity of adenosine receptors including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases.",
    "precision_class": "structural",
    "invention_explanation": "A family of fused pyrazine-based compounds that blocks selected adenosine receptors, which can help alter disease-related immune and cellular activity.",
    "technologies_mentioned": [
      "medicinal chemistry",
      "adenosine receptor inhibitors",
      "small-molecule therapeutics"
    ]
  }
}

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