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Amgen10-Q: Competitor named

Prolia & XGEVA sales fall over 30% due to biosimilar competition, losing over $540M in Q2

What happened

Sales for key drugs Prolia and XGEVA plummeted by 32% and 34% respectively in Q2 2026, a combined revenue drop of over $540 million versus prior year. This massive loss is due to patent expirations and new biosimilar competition, creating urgent pressure to optimize commercial operations and find cost efficiencies to protect margins.

Source

SEC EDGARAug 4, 2026

Quarterly report (Form 10-Q)

Amgen 10-Q

Filing excerpt

The decreases in global Prolia sales for the three and six months ended June 30, 2026 were primarily driven by lower volume of 20% and 19%, respectively, and lower net selling price of 12% and 11%, respectively.

sec.gov/Archives/edgar/data/318154/000031815426000126/amgn-20260630.htmRead the full source

Other signals in this filing (7)

Extracted by Autobound

From the Signal API record
Signal
10-Q: Competitor named

What this signalsFilings often name leadership changes, deals and spending plans.

Fiscal year end
06/30
Filed
Aug 4, 2026

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The full record

From the Signal API record

Numbers

Dollar figure
$543M (Combined Q2 YoY revenue decline for Prolia ($363M) and XGEVA ($180M))
Percent
-33% (Average YoY sales decline for Prolia (-32%) and XGEVA (-34%) in Q2)

Details

CIK
318154
Accession number
0000318154-26-000126
Timeframe
Current quarter
Filing year
2026
Fiscal year
0
Why it matters
Competitive intelligence
Signal category
Market

Topics and mentions

Competitors

  • biosimilars
  • generics

Regions named

  • United States
  • ROW

Extraction

Confidence
High
Relevance
90%
Sentiment
Negative
Detected
Aug 11, 2026
signal_type
sec-10q
signal_subtype
competitorNamed

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The API returns more than this page shows

This page shows a preview. The full sec-10q record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.

Company

  • linkedin_urlValue in the API
  • industriesValue in the API
  • employee_count_lowValue in the API
  • employee_count_highValue in the API
  • revenueValue in the API
  • descriptionValue in the API

Signal

  • signal_nameValue in the API
  • associationValue in the API
Show the full JSONThe record on this page and the API request

GET /v1/signals/e8184aea-e6b9-4d07-b144-3266739f03a1 returns this record as JSON. POST /v1/companies/enrich returns every signal for amgen.com.

{
  "signal_id": "e8184aea-e6b9-4d07-b144-3266739f03a1",
  "signal_type": "sec-10q",
  "signal_subtype": "competitorNamed",
  "detected_at": "2026-08-11T08:12:05.369+00:00",
  "company": {
    "name": "Amgen",
    "domain": "amgen.com"
  },
  "data": {
    "detail": "Sales for key drugs Prolia and XGEVA plummeted by 32% and 34% respectively in Q2 2026, a combined revenue drop of over $540 million versus prior year. This massive loss is due to patent expirations and new biosimilar competition, creating urgent pressure to optimize commercial operations and find cost efficiencies to protect margins.",
    "metrics": {
      "pct": -0.33,
      "timeframe": "current_quarter",
      "pct_context": "Average YoY sales decline for Prolia (-32%) and XGEVA (-34%) in Q2",
      "dollar_context": "Combined Q2 YoY revenue decline for Prolia ($363M) and XGEVA ($180M)",
      "dollar_millions": 543
    },
    "summary": "Prolia & XGEVA sales fall over 30% due to biosimilar competition, losing over $540M in Q2",
    "excerpts": "The decreases in global Prolia sales for the three and six months ended June 30, 2026 were primarily driven by lower volume of 20% and 19%, respectively, and lower net selling price of 12% and 11%, respectively.",
    "relevance": 0.9,
    "sentiment": "negative",
    "confidence": "high",
    "source_url": "https://www.sec.gov/Archives/edgar/data/318154/000031815426000126/amgn-20260630.htm",
    "filing_date": "2026-08-04",
    "filing_year": 2026,
    "fiscal_year": 0,
    "fiscal_year_end": "06/30",
    "sales_relevance": "Competitive intelligence",
    "signal_category": "market",
    "regions_mentioned": [
      "United States",
      "ROW"
    ],
    "competitors_mentioned": [
      "biosimilars",
      "generics"
    ]
  }
}

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