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Amgen10-Q: Market share loss

Prolia and XGEVA sales plummet over 30% due to biosimilar competition after patent expiry.

What happened

Amgen is experiencing accelerated sales erosion for two major products, Prolia (sales down 32%) and XGEVA (sales down 34%), due to lower volume and pricing from new biosimilar competitors. This significant revenue loss creates pressure to optimize operations and find efficiencies to offset the financial impact.

Source

SEC EDGARAug 4, 2026

Quarterly report (Form 10-Q)

Amgen 10-Q

Filing excerpt

The decreases in global Prolia sales for the three and six months ended June 30, 2026 were primarily driven by lower volume of 20% and 19%, respectively, and lower net selling price of 12% and 11%, respectively.

sec.gov/Archives/edgar/data/318154/000031815426000126/amgn-20260630.htmRead the full source

Other signals in this filing (7)

Extracted by Autobound

From the Signal API record
Signal
10-Q: Market share loss

What this signalsFilings often name leadership changes, deals and spending plans.

Fiscal year end
06/30
Filed
Aug 4, 2026

More 10-Q signals at other companies

The full record

From the Signal API record

Numbers

Dollar figure
$363M (Prolia quarterly sales decline YoY ($1,122M to $759M))
Percent
-32% (Prolia total sales change YoY for the quarter)

Details

CIK
318154
Accession number
0000318154-26-000126
Timeframe
Current quarter
Filing year
2026
Fiscal year
0
Why it matters
Urgency to improve

Topics and mentions

Regions named

  • United States
  • ROW
  • Europe

Extraction

Confidence
High
Relevance
90%
Sentiment
Negative
Detected
Aug 11, 2026
signal_type
sec-10q
signal_subtype
marketShareLoss

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The API returns more than this page shows

This page shows a preview. The full sec-10q record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.

Company

  • linkedin_urlValue in the API
  • industriesValue in the API
  • employee_count_lowValue in the API
  • employee_count_highValue in the API
  • revenueValue in the API
  • descriptionValue in the API

Signal

  • signal_nameValue in the API
  • associationValue in the API
Show the full JSONThe record on this page and the API request

GET /v1/signals/b804e52d-bfa7-4596-b587-08cbd141e543 returns this record as JSON. POST /v1/companies/enrich returns every signal for amgen.com.

{
  "signal_id": "b804e52d-bfa7-4596-b587-08cbd141e543",
  "signal_type": "sec-10q",
  "signal_subtype": "marketShareLoss",
  "detected_at": "2026-08-11T08:11:01.218+00:00",
  "company": {
    "name": "Amgen",
    "domain": "amgen.com"
  },
  "data": {
    "detail": "Amgen is experiencing accelerated sales erosion for two major products, Prolia (sales down 32%) and XGEVA (sales down 34%), due to lower volume and pricing from new biosimilar competitors. This significant revenue loss creates pressure to optimize operations and find efficiencies to offset the financial impact.",
    "metrics": {
      "pct": -32,
      "timeframe": "current_quarter",
      "pct_context": "Prolia total sales change YoY for the quarter",
      "dollar_context": "Prolia quarterly sales decline YoY ($1,122M to $759M)",
      "dollar_millions": 363
    },
    "summary": "Prolia and XGEVA sales plummet over 30% due to biosimilar competition after patent expiry.",
    "excerpts": "The decreases in global Prolia sales for the three and six months ended June 30, 2026 were primarily driven by lower volume of 20% and 19%, respectively, and lower net selling price of 12% and 11%, respectively.",
    "relevance": 0.9,
    "sentiment": "negative",
    "confidence": "high",
    "source_url": "https://www.sec.gov/Archives/edgar/data/318154/000031815426000126/amgn-20260630.htm",
    "filing_date": "2026-08-04",
    "filing_year": 2026,
    "fiscal_year": 0,
    "fiscal_year_end": "06/30",
    "sales_relevance": "Urgency to improve",
    "signal_category": "market",
    "regions_mentioned": [
      "United States",
      "ROW",
      "Europe"
    ]
  }
}

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