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Bristol Myers SquibbPatent grant

Bristol-Myers Squibb was granted a patent for anti-CCR8 cancer antibodies.

What happened

In September 2026 Bristol-Myers Squibb patented antibody treatments for targeting CCR8-bearing cells in cancer therapy, either alone or alongside other treatments.

Source

patents.google.comSep 29, 2026

US patent US12747296

Anti-CCR8 antibodies for treating cancer

Abstract

This disclosure provides isolated antibodies, for example, monoclonal antibodies, that specifically bind to the C-C Motif Chemokine Receptor 8 (CCR8) expressed on the surface of a cell and mediate depletion of the CCR8-expressing cell by anti-body-dependent cellular cytotoxicity (ADCC). The disclosure provides methods for treating a subject afflicted with a cancer comprising administering to the subject a therapeutically effective amount of an anti-CCR8 antibody as monotherapy or in combination with an anti-cancer agent such as an immune checkpoint inhibitor, for example, an anti-PD-1 or anti-PD-L1 antibody.

patents.google.com/patent/US12747296Read the full source

Extracted by Autobound

From the Signal API record
Signal
Patent grant

What this signalsA new patent often shows where a company is putting its R&D budget.

Grant date
Sep 29, 2026
Inventors
4
Patent number
US12747296
Assignee
BRISTOL-MYERS SQUIBB COMPANY

The full record

From the Signal API record

People

  • Ruth Yin-Zong LanInventor
  • Olufemi A. AdelakunInventor
  • Ishita BarmanInventor
  • Joseph Richard CampbellInventor
  • SJ Jian Zhe DiongInventor
  • Felix FindeisenInventor

Details

Primary CPC class
C07K 16/2866
USPTO assignee
BRISTOL-MYERS SQUIBB COMPANY
What the invention does
An antibody that attaches to CCR8 on cancer-associated cells and helps the immune system destroy those cells through antibody-dependent cellular cytotoxicity.

Topics and mentions

Tags

  • Intellectual Property
  • Research & Development
  • Pharmaceuticals
  • Medical Research

Technologies named

  • monoclonal antibodies
  • immuno-oncology
  • antibody-dependent cellular cytotoxicity
  • CCR8 targeting

Extraction

Detected
Sep 30, 2026
signal_type
patents-company
signal_subtype
patentGrant

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This page shows a preview. The full patents-company record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.

Company

  • linkedin_urlValue in the API
  • industriesValue in the API
  • employee_count_lowValue in the API
  • employee_count_highValue in the API
  • revenueValue in the API
  • descriptionValue in the API

Signal

  • signal_nameValue in the API
  • associationValue in the API
Show the full JSONThe record on this page and the API request

GET /v1/signals/e5236222-ed5a-51fb-a064-f357ec4b6ec9 returns this record as JSON. POST /v1/companies/enrich returns every signal for bms.com.

{
  "signal_id": "e5236222-ed5a-51fb-a064-f357ec4b6ec9",
  "signal_type": "patents-company",
  "signal_subtype": "patentGrant",
  "detected_at": "2026-09-30T16:59:17+00:00",
  "company": {
    "name": "Bristol Myers Squibb",
    "domain": "bms.com"
  },
  "data": {
    "cpc": [
      {
        "code": "C07K 16/2866"
      },
      {
        "code": "A61P 35/00"
      },
      {
        "code": "C07K 16/2818"
      },
      {
        "code": "A61K 2039/505"
      },
      {
        "code": "A61K 2039/507"
      }
    ],
    "tags": [
      "Intellectual Property",
      "Research & Development",
      "Pharmaceuticals",
      "Medical Research"
    ],
    "detail": "In September 2026 Bristol-Myers Squibb patented antibody treatments for targeting CCR8-bearing cells in cancer therapy, either alone or alongside other treatments.",
    "summary": "Bristol-Myers Squibb was granted a patent for anti-CCR8 cancer antibodies.",
    "event_at": "2026-09-29",
    "inventors": [
      {
        "name": "Ruth Yin-Zong Lan",
        "status": "resolved",
        "is_primary": true,
        "linkedin_url": "https://www.linkedin.com/in/ruth-lan-23171a20"
      },
      {
        "name": "Olufemi A. Adelakun",
        "status": "unresolved",
        "is_primary": false
      },
      {
        "name": "Ishita Barman",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/ishitabarman"
      },
      {
        "name": "Joseph Richard Campbell",
        "status": "unresolved",
        "is_primary": false
      },
      {
        "name": "SJ Jian Zhe Diong",
        "status": "unresolved",
        "is_primary": false
      },
      {
        "name": "Felix Findeisen",
        "status": "unresolved",
        "is_primary": false
      },
      {
        "name": "Danielle M. Greenawalt",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/daniellegreenawalt"
      },
      {
        "name": "Renu Jain",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/renu-jain-67195b1b"
      }
    ],
    "event_kind": "grant_date",
    "grant_date": "2026-09-29",
    "source_url": "https://patents.google.com/patent/US12747296",
    "cpc_primary": {
      "code": "C07K 16/2866"
    },
    "patent_title": "Anti-CCR8 antibodies for treating cancer",
    "patent_number": "US12747296",
    "uspto_assignee": "BRISTOL-MYERS SQUIBB COMPANY",
    "patent_abstract": "This disclosure provides isolated antibodies, for example, monoclonal antibodies, that specifically bind to the C-C Motif Chemokine Receptor 8 (CCR8) expressed on the surface of a cell and mediate depletion of the CCR8-expressing cell by anti-body-dependent cellular cytotoxicity (ADCC). The disclosure provides methods for treating a subject afflicted with a cancer comprising administering to the subject a therapeutically effective amount of an anti-CCR8 antibody as monotherapy or in combination with an anti-cancer agent such as an immune checkpoint inhibitor, for example, an anti-PD-1 or anti-PD-L1 antibody.",
    "precision_class": "structural",
    "invention_explanation": "An antibody that attaches to CCR8 on cancer-associated cells and helps the immune system destroy those cells through antibody-dependent cellular cytotoxicity.",
    "technologies_mentioned": [
      "monoclonal antibodies",
      "immuno-oncology",
      "antibody-dependent cellular cytotoxicity",
      "CCR8 targeting"
    ]
  }
}

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