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Bristol Myers SquibbPatent grant

Bristol-Myers Squibb was granted a patent for BTK-inhibiting compounds.

What happened

In October 2026 Bristol-Myers Squibb patented drug candidates for treating autoimmune and vascular diseases through targeted pharmaceutical therapies.

Source

patents.google.comOct 13, 2026

US patent US12759999

Indole carboxamide compounds

Abstract

Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR 4 or N; R 1, R 2, R 3, R 4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.

patents.google.com/patent/US12759999Read the full source

Extracted by Autobound

From the Signal API record
Signal
Patent grant

What this signalsA new patent often shows where a company is putting its R&D budget.

Grant date
Oct 13, 2026
Inventors
4
Patent number
US12759999
Assignee
Bristol-Myers Squibb Company

The full record

From the Signal API record

People

  • Qingjie LiuInventor
  • Scott Hunter WattersonInventor
  • John E. MacorInventor
  • Khehyong NguInventor
  • Saleem AhmadInventor

Details

Primary CPC class
C07D 401/10
USPTO assignee
Bristol-Myers Squibb Company
What the invention does
A family of indole-based chemical compounds designed to block Bruton's tyrosine kinase, a protein involved in immune-cell signaling.

Topics and mentions

Tags

  • Intellectual Property
  • Research & Development
  • Pharmaceuticals
  • Medical Research

Technologies named

  • medicinal chemistry
  • BTK inhibitors
  • pharmaceutical compositions

Extraction

Detected
Oct 14, 2026
signal_type
patents-company
signal_subtype
patentGrant

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The API returns more than this page shows

This page shows a preview. The full patents-company record in the Signal API and MCP can also have these 8 fields. Some fields are empty for some signals.

Company

  • linkedin_urlValue in the API
  • industriesValue in the API
  • employee_count_lowValue in the API
  • employee_count_highValue in the API
  • revenueValue in the API
  • descriptionValue in the API

Signal

  • signal_nameValue in the API
  • associationValue in the API
Show the full JSONThe record on this page and the API request

GET /v1/signals/15cdaaef-6290-59cf-98ee-319b3de00fd4 returns this record as JSON. POST /v1/companies/enrich returns every signal for bms.com.

{
  "signal_id": "15cdaaef-6290-59cf-98ee-319b3de00fd4",
  "signal_type": "patents-company",
  "signal_subtype": "patentGrant",
  "detected_at": "2026-10-14T15:26:40+00:00",
  "company": {
    "name": "Bristol Myers Squibb",
    "domain": "bms.com"
  },
  "data": {
    "cpc": [
      {
        "code": "C07D 401/10"
      },
      {
        "code": "A61P 29/00"
      },
      {
        "code": "A61P 37/00"
      },
      {
        "code": "C07D 209/08"
      },
      {
        "code": "C07D 209/18"
      }
    ],
    "tags": [
      "Intellectual Property",
      "Research & Development",
      "Pharmaceuticals",
      "Medical Research"
    ],
    "detail": "In October 2026 Bristol-Myers Squibb patented drug candidates for treating autoimmune and vascular diseases through targeted pharmaceutical therapies.",
    "summary": "Bristol-Myers Squibb was granted a patent for BTK-inhibiting compounds.",
    "event_at": "2026-10-13",
    "inventors": [
      {
        "name": "Qingjie Liu",
        "status": "unresolved",
        "is_primary": true
      },
      {
        "name": "Scott Hunter Watterson",
        "status": "unresolved",
        "is_primary": false
      },
      {
        "name": "John E. Macor",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/john-e-macor-7557b211"
      },
      {
        "name": "Khehyong Ngu",
        "status": "resolved",
        "is_primary": false,
        "linkedin_url": "https://www.linkedin.com/in/khehyong-ngu-7b223810"
      },
      {
        "name": "Saleem Ahmad",
        "status": "unresolved",
        "is_primary": false
      }
    ],
    "event_kind": "grant_date",
    "grant_date": "2026-10-13",
    "source_url": "https://patents.google.com/patent/US12759999",
    "cpc_primary": {
      "code": "C07D 401/10"
    },
    "patent_title": "Indole carboxamide compounds",
    "patent_number": "US12759999",
    "uspto_assignee": "Bristol-Myers Squibb Company",
    "patent_abstract": "Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR 4 or N; R 1 , R 2 , R 3 , R 4 , and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.",
    "precision_class": "structural",
    "invention_explanation": "A family of indole-based chemical compounds designed to block Bruton's tyrosine kinase, a protein involved in immune-cell signaling.",
    "technologies_mentioned": [
      "medicinal chemistry",
      "BTK inhibitors",
      "pharmaceutical compositions"
    ]
  }
}

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