What you should know about the new mRNA flu vaccine
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You are free to share this article under the Attribution 4.0 International license. The FDA's approval of an mRNA flu shot presents a new, long-awaited option - and raises big questions about the future of flu vaccines. On August 5, the US Food and Drug Administration approved Moderna's mFLUSIVA, the first influenza vaccine to use mRNA technology, for adults 50 and older. The approval gives many older Americans a long-awaited new option for protection. Tens of thousands of Americans typically die from the flu every year, and the vast majority of them are 65 and older. It's long been a public health priority to evolve flu vaccine technology - a process which currently takes more than six months to produce a shot and is prone to mismatches with the circulating strains - so that manufacturers can respond more quickly to the evolving virus, ultimately making flu shots more effective. When it comes to those goals, Moderna's mRNA shot is "very, very promising," says Anna Durbin, a professor in the international health department at Johns Hopkins University and director of the Center for Immunization Research. "Most vaccinologists believe that mRNA vaccines are the future," says Durbin, who sits on the FDA panel that recommended the vaccine. Regulators in the EU, Canada, and Australia are also reviewing the vaccine, and the European Medicine Agency has separately authorized a...
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